Distribusjonsvolumet vil være ca. 5 liter hos et voksent menneske for et legemiddel som hovedsakelig befinner seg i plasma. ninety % ved samtidig bruk av rifampicin, at den reduseres med ca. 70 % ved samtidig bruk av rifapentin (daglig dosering), og at den reduseres med 30-forty % samtidig

Unwanted effects, if occur, are typically observed at the start of therapy and usually disappear on continued medication. The metabolism of alprazolam is mediated mainly through the motion of CYP3As and so alprazolam is contraindicated with CYP3A inhibitors which include ketoconazole and itracona

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